diff --git a/src/Umbraco.Core/Persistence/Migrations/Upgrades/TargetVersionSevenFiveZero/UpdateUniqueIndexOnCmsPropertyData.cs b/src/Umbraco.Core/Persistence/Migrations/Upgrades/TargetVersionSevenFiveZero/UpdateUniqueIndexOnCmsPropertyData.cs
index 0896af42e7..4bae9c80e4 100644
--- a/src/Umbraco.Core/Persistence/Migrations/Upgrades/TargetVersionSevenFiveZero/UpdateUniqueIndexOnCmsPropertyData.cs
+++ b/src/Umbraco.Core/Persistence/Migrations/Upgrades/TargetVersionSevenFiveZero/UpdateUniqueIndexOnCmsPropertyData.cs
@@ -33,7 +33,24 @@ namespace Umbraco.Core.Persistence.Migrations.Upgrades.TargetVersionSevenFiveZer
 
             if (found != null)
             {
-                Execute.Sql("DELETE FROM cmsPropertyData WHERE id NOT IN (SELECT MIN(id) FROM cmsPropertyData GROUP BY contentNodeId, versionId, propertytypeid HAVING MIN(id) IS NOT NULL)");
+                //Check for MySQL
+                if (Context.CurrentDatabaseProvider == DatabaseProviders.MySql)
+                {
+                    //Use the special double nested sub query for MySQL since that is the only
+                    //way delete sub queries works
+                    SqlSyntax.GetDeleteSubquery(
+                        "cmsPropertyData",
+                        "id",
+                        new Sql("SELECT MIN(id) FROM cmsPropertyData GROUP BY contentNodeId, versionId, propertytypeid HAVING MIN(id) IS NOT NULL"),
+                        WhereInType.NotIn);
+                }
+                else
+                {
+                    //NOTE: Even though the above will work for MSSQL, we are not going to execute the
+                    // nested delete sub query logic since it will be slower and there could be a ton of property 
+                    // data here so needs to be as fast as possible.
+                    Execute.Sql("DELETE FROM cmsPropertyData WHERE id NOT IN (SELECT MIN(id) FROM cmsPropertyData GROUP BY contentNodeId, versionId, propertytypeid HAVING MIN(id) IS NOT NULL)");
+                }
 
                 //we need to re create this index
                 Delete.Index("IX_cmsPropertyData_1").OnTable("cmsPropertyData");
diff --git a/src/Umbraco.Core/Persistence/SqlSyntax/SqlSyntaxProviderExtensions.cs b/src/Umbraco.Core/Persistence/SqlSyntax/SqlSyntaxProviderExtensions.cs
index af18d9c3d9..1231765f20 100644
--- a/src/Umbraco.Core/Persistence/SqlSyntax/SqlSyntaxProviderExtensions.cs
+++ b/src/Umbraco.Core/Persistence/SqlSyntax/SqlSyntaxProviderExtensions.cs
@@ -22,12 +22,23 @@
         /// <remarks>
         /// See: http://issues.umbraco.org/issue/U4-3876
         /// </remarks>
-        public static Sql GetDeleteSubquery(this ISqlSyntaxProvider sqlProvider, string tableName, string columnName, Sql subQuery)
+        public static Sql GetDeleteSubquery(this ISqlSyntaxProvider sqlProvider, string tableName, string columnName, Sql subQuery, WhereInType whereInType = WhereInType.In)
         {
-            return new Sql(string.Format(@"DELETE FROM {0} WHERE {1} IN (SELECT {1} FROM ({2}) x)",
+
+            return 
+                new Sql(string.Format(
+                    whereInType == WhereInType.In
+                        ? @"DELETE FROM {0} WHERE {1} IN (SELECT {1} FROM ({2}) x)"
+                        : @"DELETE FROM {0} WHERE {1} NOT IN (SELECT {1} FROM ({2}) x)",
                 sqlProvider.GetQuotedTableName(tableName),
                 sqlProvider.GetQuotedColumnName(columnName),
                 subQuery.SQL), subQuery.Arguments);
         }
     }
+
+    internal enum WhereInType
+    {
+        In,
+        NotIn
+    }
 }
\ No newline at end of file